Publikationen Dr. Philipp Westhofen

  • Caspers M, Czogalla KJ, Liphardt K, Müller J, Westhofen P, Watzka M, Oldenburg J. Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly  expressed in exocrine tissues while VKORC1L1 is highly expressed in brain. Thromb Res. 2015 Jan 26. pii: S0049- 3848(15)00043-2.
  • Ivaškevičius V, Goldmann G, Biswas A, Westhofen P, Thomas A, Marquardt N, Horneff S, Klein C, Rühl H, Pötzsch B, Oldenburg J. Neoplasm-induced bleeding in inherited, heterozygous FXIII-A deficiency. Hamostaseologie. 2015;35 Suppl 1:S32-5.
  • Czogalla KJ,  Biswas A, Wendeln AC, Westhofen P,  Müller CR, Watzka M, Oldenburg J. Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces. Blood. 2013 Oct 10;122(15):2743-50.
  • Marinova M, Lütjohann D, Breuer O, Kölsch H, Westhofen P, Watzka M, Mengel M, Stoffel- Wagner B, Hartmann G, Coch C, Oldenburg J. VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation. Eur J Clin Pharmacol. 2013 Mar;69(3):467-75. doi: 10.1007/s00228-012-1362-y. Epub 2012 Aug 5.
  • Westhofen P,  Watzka M, Marinova M, Hass M. Kirfel G, Müller J, Bevans CG, Müller CR, Oldenburg J. Human vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1) mediates vitamin K-dependent intracellular antioxidant function. J Biol Chem. 2011 Apr 29;286(17):15085-94.
  • Watzka M, Westhofen P, Hass M, Marinova M, Pötzsch B, Oldenburg J. Polymorphisms in VKORC1 and GGCX are not major genetic determinants of vitamin K-dependent coagulation factor activity in Western Germans. Thromb Haemost. 2009 Aug;102(2):418-20. doi: 10.1160/TH09-04-0217.
  • Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study.
  • Chaudhry SR, Lendvai IS, Muhammad S, Westhofen P, Kruppenbacher J, Scheef L, Boecker H, Scheele D, Hurlemann R, Kinfe TM.
  • Brain Stimul. 2019 May - Jun;12(3):643-651. doi: 10.1016/j.brs.2019.01.008. Epub 2019 Jan 19.

PMID:30745260

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